Here's a refreshing, summery twist on an old favorite. Try it with honeydew, substituting lime juice for the lemon, and Midori liqueur for the limoncello.
Place the melon, ice, lemon juice, and sugar in a blender and process until smooth. Add the tequila and limoncello and blend for 10 seconds.
Rub the rims of 4 glasses with the lemon wedges. Place a layer of salt or sugar (depending on your preference) on a small plate. Dip the moistened rim of each glass in the salt or sugar.
Carefully divide the margarita mixture among the glasses. Garnish with mint sprigs, if desired.